It is mistaken to claim that global problems will be solved more quickly if only researchers would abandon their quest to understand the universe and knuckle down to work on an agenda of public or political concerns. These are not 'either/or' options - indeed, there is a positive symbiosis between them.
— Martin Rees
Manufacturing doesn't just mean building cars and metal-bashing; it includes making pharmaceuticals and hi-tech electronics. A crucial part of the process is the research and development that allows better and greener products to come to market. Britain has traditionally had a strong science and engineering base.
And we should keep our minds open, or at least ajar, to concepts on the fringe of science fiction. Flaky American futurologists aren't always wrong. They remind us that a superintelligent machine is the last instrument that humans may ever design - the machine will itself take over in making further steps.
Stars that become supernovae start off at least eight times heavier than our sun. They're so short-lived that, even if they have planets, there is unlikely to be time for life to get started. The surface is 40,000C and, as a result, the colouring will be extremely blue.
From the growth of the Internet through to the mapping of the human genome and our understanding of the human brain, the more we understand, the more there seems to be for us to explore.
There's now, for the first time, a huge gulf between the artefacts of our everyday life and what even a single expert, let alone the average child, can comprehend. The gadgets that now pervade young people's lives, iPhones and suchlike, are baffling 'black boxes' - pure magic to most people.
Manned spaceflight has lost its glamour - understandably so, because it hardly seems inspiring, 40 years after Apollo, for astronauts merely to circle the Earth in the space shuttle and the International Space Station.
It's often better to read first-rate science fiction than second-rate science - it's far more stimulating, and perhaps no more likely to be wrong.
We know too little about how life began on Earth to lay confident odds. It may have involved a fluke so rare that it happened only once in the entire galaxy. On the other hand, it may have been almost inevitable, given the right environment.
If you represent the Earth's lifetime by a single year, say from January when it was made to December, the 21st-century would be a quarter of a second in June - a tiny fraction of the year. But even in this concertinaed cosmic perspective, our century is very, very special: the first when humans can change themselves and their home planet.
If you take 10,000 people at random, 9,999 have something in common: their interests in business lie on or near the Earth's surface. The odd one out is an astronomer, and I am one of that strange breed.
Devastation could arise insidiously, rather than suddenly, through unsustainable pressure on energy supplies, food, water and other natural resources. Indeed, these pressures are the prime 'threats without enemies' that confront us.
It's important that everyone realizes how much scientists still don't know.
In future, children won't perceive the stars as mere twinkling points of light: they'll learn that each is a 'Sun', orbited by planets fully as interesting as those in our Solar system.
Scientists surely have a special responsibility. It is their ideas that form the basis of new technology. They should not be indifferent to the fruits of their ideas. They should forgo experiments that are risky or unethical.
The U.S., France, Germany and Canada have all responded to the financial crisis by boosting rather than cutting their science funding. The U.K. has not.
Scientists habitually moan that the public doesn't understand them. But they complain too much: public ignorance isn't peculiar to science. It's sad if some citizens can't tell a proton from a protein. But it's equally sad if they're ignorant of their nation's history, can't speak a second language, or can't find Venezuela or Syria on a map.
The scientific community should work as hard as possible to address major issues that affect our everyday lives such as climate change, infectious diseases and counterterrorism; in particular, 'clean energy' research deserves far higher priority. And science and technology are the prime routes to tackling these issues.
To ensure continuing prosperity in the global economy, nothing is more important than the development and application of knowledge and skills.
The most important advances, the qualitative leaps, are the least predictable. Not even the best scientists predicted the impact of nuclear physics, and everyday consumer items such as the iPhone would have seemed magic back in the 1950s.
Whether it is to reduce our carbon-dioxide emissions or to prepare for when the coal and oil run out, we have to continue to seek out new energy sources.
Issues relating to global health and sustainability must stay high on the agenda if we are to cope with an ageing and ever-increasing population, with growing pressure on resources, and with rising global temperatures. The risks and dangers need to be assessed and then confronted.
The Swedish engineer who invented the zip fastener made a greater intellectual leap than many scientists do in a lifetime.
The images of Earth's delicate biosphere, contrasting with the sterile moonscape where the astronauts left their footsteps, have become iconic for environmentalists: these may indeed be the Apollo programme's most enduring legacy.
Maybe the search for life shouldn't restrict attention to planets like Earth. Science fiction writers have other ideas: balloon-like creatures floating in the dense atmospheres of planets such as Jupiter, swarms of intelligent insects, nano-scale robots and more.
Some global hazards are insidious. They stem from pressure on energy supplies, food, water and other natural resources. And they will be aggravated as the population rises to a projected nine billion by mid-century, and by the effects of climate change. An 'ecological shock' could irreversibly degrade our environment.
In our interconnected world, novel technology could empower just one fanatic, or some weirdo with a mindset of those who now design computer viruses, to trigger some kind of disaster. Indeed, catastrophe could arise simply from technical misadventure - error rather than terror.
I have no religious belief myself, but I don't think we should fight about it. In particular, I think that we should not rubbish moderate religious leaders like the Archbishop of Canterbury because I think we all agree that extreme fundamentalism is a threat, and we need all the allies we can muster against it.
I think a few hundred years from now we'll start having the 'posthuman' era of different species.
Science isn't just for scientists - it's not just a training for careers.
All space projects push the frontiers of technology and are drivers of innovation.
Some claim that computers will, by 2050, achieve human capabilities. Of course, in some respects they already have.
Science shouldn't be just for scientists, and there are encouraging signs that it is becoming more pervasive in culture and the media.
Campaigning against religion can be socially counter-productive. If teachers take the uncompromising line that God and Darwinism are irreconcilable, many young people raised in a faith-based culture will stick with their religion and be lost to science.
One of President Obama's first acts was to give a massive boost to America's scientific community.
Ever since Darwin, we've been familiar with the stupendous timespans of the evolutionary past. But most people still somehow think we humans are necessarily the culmination of the evolutionary tree. No astronomer could believe this.
Computer power grows according to Moore's law, as does the sophistication of handheld devices.
From a personal perspective, I am disappointed that we have yet to really achieve a full understanding of the origins of life on Earth. What was the spark that, billions of years ago, kickstarted the process of evolution that has brought us life as we know it today? I hope that we will get some answers to that in my lifetime.
Crucial to science education is hands-on involvement: showing, not just telling; real experiments and field trips and not just 'virtual reality.'
It is foolish to claim, as some do, that emigration into space offers a long-term escape from Earth's problems. Nowhere in our solar system offers an environment even as clement as the Antarctic or the top of Everest.
The first arrival of earthly life on another celestial body ranks as an epochal event not only for our generation, but in the history of our planet. Neil Armstrong was at the cusp of the Apollo programme. This was a collective technological effort of epic scale, but his is the one name sure to be remembered centuries hence.
Indeed, evolutionists don't agree on how divergently our own biosphere could have developed if such contingencies as ice ages and meteorite impacts had happened differently.
Over most of history, threats have come from nature - disease, earthquakes, floods, and so forth. But the worst now come from us. We've entered a geological era called the anthropocene. This started, perhaps, with the invention of thermonuclear weapons.
We can trace things back to the earlier stages of the Big Bang, but we still don't know what banged and why it banged. That's a challenge for 21st-century science.
We need to broaden our sympathies both in space and time - and perceive ourselves as part of a long heritage, and stewards for an immense future.
The 'clean energy' challenge deserves a commitment akin to the Manhattan project or the Apollo moon landing.
I'm not myself religious but have no wish to insult or denigrate those who are.
To most people in the U.K., indeed throughout Western Europe, space exploration is primarily perceived as 'what NASA does'. This perception is - in many respects - a valid one. Superpower rivalry during the Cold War ramped up U.S. and Soviet space efforts to a scale that Western Europe had no motive to match.
I hope that by 2050 the entire solar system will have been explored and mapped by flotillas of tiny robotic craft.
The extreme sophistication of modern technology - wonderful though its benefits are - is, ironically, an impediment to engaging young people with basics: with learning how things work.