I had always thought of myself as fairly tough and fairly strong and fairly able to cope with anything. And then I had a series of personal losses. My mother died. A relationship that I was in came to end, and a variety of other things went awry.

Kids with Down syndrome are, by and large, quite affectionate and relatively guileless, and frequently, the attachments to them grow and deepen. And the meaning that parents find in it grows and deepens.

One of the things that frequently gets lost in descriptions of depression is that the depressed person often knows that it is a ludicrous condition to feel so disabled by the ordinary business of quotidian life.

Andrew Solomon Quotes