People who look for the first time through a microscope say, 'Now I see this, and then I see that,' and even a skilled observer can be fooled. On these observations I have spent more time than many will believe, but I have done them with joy, and I have taken no notice of those who have said, 'Why take so much trouble,' and, 'What good is it?'
— Antonie van Leeuwenhoek