Just as much as the United States mattered to cotton, cotton mattered to the United States. Cotton reinvigorated slavery, established the young nation's place in the global economy, and eventually helped create the political and economic conflicts that resulted in civil war.

Harriet Washington, in 'Medical Apartheid: The Dark History of Medical Experimentation on Black Americans from Colonial Times to the Present,' documents the smallpox experiments Thomas Jefferson performed on his Monticello slaves. In fact, much of what we now think of as public health emerged from the slave system.

Starting in the early 1800s, Southerners in the United States began to defend slavery as their 'peculiar institution,' and northerners didn't mind, since the phrase suggested that chattel bondage was quarantined from the rest of the nation: that it was, or soon would be, a relic of its past and would not define its future.

Greg Grandin Quotes