In the early 16th century the Italian physician Jacopo Berengario da Carpi, a pioneer in the science of anatomy, came up with the idea that perhaps 'brain commotion' was caused by the thrust of the soft structure of the brain against the solid case of the skull.

If chronic bashing of the head could destroy a boxer's brain, couldn't it also destroy a football player's brain? Surely someone in the history of football had thought to look for dementia pugilistica. Unlike boxers, football players wear helmets, but a helmet can't fully protect the head from damaging impact.

The brain is suspended in a kind of thick jelly inside the skull, and a helmet can't keep it from sloshing around. If you hit your head hard enough, the brain goes bashing against the walls of the skull.

Jeanne Marie Laskas Quotes