Immunologists agreed that an individual vertebrate synthesizes many millions of structurally different forms of antibody molecules even before it encounters an antigen.

Although we often discussed the idea of research on the nature of antigen recognition by T cells in the laboratory in the late Seventies while I was still in Basel, the real work did not start until the early Eighties in my new laboratory at M.I.T.

In the early Seventies, the technology for purifying a specific eukaryotic mRNA was just becoming available.

Susumu Tonegawa Quotes